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- Title
Reverting antibiotic tolerance of Pseudomonas aeruginosa PAO1 persister cells by (Z)-4-bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one.
- Authors
Pan, Jiachuan; Bahar, Ali Adem; Syed, Haseeba; Ren, Dacheng
- Abstract
Bacteria are well known to form dormant persister cells that are tolerant to most antibiotics. Such intrinsic tolerance also facilitates the development of multidrug resistance through acquired mechanisms. Thus persister cells are a promising target for developing more effective methods to control chronic infections and help prevent the development of multidrug-resistant bacteria. However, control of persister cells is still an unmet challenge.
- Publication
PloS one, 2012, Vol 7, Issue 9, pe45778
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0045778