We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Tenofovir use and renal insufficiency among pregnant and general adult population of HIV-infected, ART-naïve individuals in Lilongwe, Malawi.
- Authors
Johnson, Derek C; Chasela, Charles; Maliwichi, Madalitso; Mwafongo, Albert; Akinkuotu, Adesola; Moses, Agness; Jamieson, Denise J; Kourtis, Athena P; King, Caroline C; van der Horst, Charlie; Hosseinipour, Mina C
- Abstract
The Malawian government recently changed its prevention of mother-to-child transmission (PMTCT) regimen and plans to change its first-line antiretroviral therapy (ART) regimen to Tenofovir(TDF)/Lamivudine/Efavirenz as a fixed-dose combination tablet. Implementation could be challenging if baseline creatinine clearance (CrCl) screening were required to assess renal function prior to TDF therapy. Our goal is to determine predictors of CrCl<50 ml/min among HIV-infected, ART-naïve individuals.
- Publication
PloS one, 2012, Vol 7, Issue 7, pe41011
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0041011