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- Title
Are there neurophenotypes for asthma? Functional brain imaging of the interaction between emotion and inflammation in asthma.
- Authors
Rosenkranz, Melissa A; Busse, William W; Sheridan, John F; Crisafi, Gina M; Davidson, Richard J
- Abstract
Asthma is a chronic inflammatory disease noteworthy for its vulnerability to stress and emotion-induced symptom intensification. The fact that psychological stress and mood and anxiety disorders appear to increase expression of asthma symptoms suggests that neural signaling between the brain and lung at least partially modulates the inflammatory response and lung function. However, the precise nature of the neural pathways implicated in modulating asthma symptoms is unknown. Moreover, the extent to which variations in neural signaling predict different phenotypes of disease expression has not been studied.
- Publication
PloS one, 2012, Vol 7, Issue 8, pe40921
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0040921