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- Title
Myeloid suppressor cell depletion augments antitumor activity in lung cancer.
- Authors
Srivastava, Minu K; Zhu, Li; Harris-White, Marni; Kar, Upendra K; Huang, Min; Johnson, Ming F; Lee, Jay M; Elashoff, David; Strieter, Robert; Dubinett, Steven; Sharma, Sherven
- Abstract
Myeloid derived suppressor cells (MDSC) are important regulators of immune responses. We evaluated the mechanistic role of MDSC depletion on antigen presenting cell (APC), NK, T cell activities and therapeutic vaccination responses in murine models of lung cancer.
- Publication
PloS one, 2012, Vol 7, Issue 7, pe40677
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0040677