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- Title
Genomic assessment of human cumulus cell marker genes as predictors of oocyte developmental competence: impact of various experimental factors.
- Authors
Feuerstein, Prisca; Puard, Vincent; Chevalier, Catherine; Teusan, Raluca; Cadoret, Veronique; Guerif, Fabrice; Houlgatte, Remi; Royere, Dominique
- Abstract
Single embryo transfer (SET) is the most successful way to reduce the frequency of multiple pregnancies following in vitro fertilisation. However, selecting the embryo for SET with the highest chances of pregnancy remains a difficult challenge since morphological and kinetics criteria provide poor prediction of both developmental and implantation ability. Partly through the expression of specific genes, the oocyte-cumulus interaction helps the oocyte to acquire its developmental competence. Our aim was therefore to identify at the level of cumulus cells (CCs) genes related to oocyte developmental competence.
- Publication
PloS one, 2012, Vol 7, Issue 7, pe40449
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0040449