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- Title
High confidence prediction of essential genes in Burkholderia cenocepacia.
- Authors
Juhas, Mario; Stark, Manuel; von Mering, Christian; Lumjiaktase, Puthapoom; Crook, Derrick W; Valvano, Miguel A; Eberl, Leo
- Abstract
Essential genes are absolutely required for the survival of an organism. The identification of essential genes, besides being one of the most fundamental questions in biology, is also of interest for the emerging science of synthetic biology and for the development of novel antimicrobials. New antimicrobial therapies are desperately needed to treat multidrug-resistant pathogens, such as members of the Burkholderia cepacia complex.
- Publication
PloS one, 2012, Vol 7, Issue 6, pe40064
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0040064