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- Title
Molecular epidemiology of HIV-1 subtypes in India: origin and evolutionary history of the predominant subtype C.
- Authors
Neogi, Ujjwal; Bontell, Irene; Shet, Anita; De Costa, Ayesha; Gupta, Soham; Diwan, Vishal; Laishram, Ranbir S; Wanchu, Ajay; Ranga, Udaykumar; Banerjea, Akhil C; Sönnerborg, Anders
- Abstract
India has the third largest HIV-1 epidemic with 2.4 million infected individuals. Molecular epidemiological analysis has identified the predominance of HIV-1 subtype C (HIV-1C). However, the previous reports have been limited by sample size, and uneven geographical distribution. The introduction of HIV-1C in India remains uncertain due to this lack of structured studies. To fill the gap, we characterised the distribution pattern of HIV-1 subtypes in India based on data collection from nationwide clinical cohorts between 2007 and 2011. We also reconstructed the time to the most recent common ancestor (tMRCA) of the predominant HIV-1C strains.
- Publication
PloS one, 2012, Vol 7, Issue 6, pe39819
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0039819