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- Title
Potential of host markers produced by infection phase-dependent antigen-stimulated cells for the diagnosis of tuberculosis in a highly endemic area.
- Authors
Chegou, Novel N; Essone, Paulin N; Loxton, Andre G; Stanley, Kim; Black, Gillian F; van der Spuy, Gian D; van Helden, Paul D; Franken, Kees L; Parida, Shreemanta K; Klein, Michel R; Kaufmann, Stefan H E; Ottenhoff, Tom H M; Walzl, Gerhard
- Abstract
Recent interferon gamma (IFN-γ)-based studies have identified novel Mycobacterium tuberculosis (M.tb) infection phase-dependent antigens as diagnostic candidates. In this study, the levels of 11 host markers other than IFN-γ, were evaluated in whole blood culture supernatants after stimulation with M.tb infection phase-dependent antigens, for the diagnosis of TB disease.
- Publication
PloS one, 2012, Vol 7, Issue 6, pe38501
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0038501