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- Title
Phase I study of cetuximab, irinotecan, and vandetanib (ZD6474) as therapy for patients with previously treated metastastic colorectal cancer.
- Authors
Meyerhardt, Jeffrey A; Ancukiewicz, Marek; Abrams, Thomas A; Schrag, Deborah; Enzinger, Peter C; Chan, Jennifer A; Kulke, Matthew H; Wolpin, Brian M; Goldstein, Michael; Blaszkowsky, Lawrence; Zhu, Andrew X; Elliott, Meaghan; Regan, Eileen; Jain, Rakesh K; Duda, Dan G
- Abstract
To determine the maximum tolerated dose (MTD) and safety, and explore efficacy and biomarkers of vandetanib with cetuximab and irinotecan in second-line metastatic colorectal cancer.
- Publication
PloS one, 2012, Vol 7, Issue 6, pe38231
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0038231