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- Title
Impact of natalizumab on cognitive performances and fatigue in relapsing multiple sclerosis: a prospective, open-label, two years observational study.
- Authors
Iaffaldano, Pietro; Viterbo, Rosa Gemma; Paolicelli, Damiano; Lucchese, Guglielmo; Portaccio, Emilio; Goretti, Benedetta; Direnzo, Vita; D'Onghia, Mariangela; Zoccolella, Stefano; Amato, Maria Pia; Trojano, Maria
- Abstract
Natalizumab reduces the relapse rate and magnetic resonance imaging activity in patients with Relapsing-Remitting Multiple Sclerosis (RRMS). So far the influence of natalizumab on cognitive functions and fatigue in MS remains uncertain. The aim of this prospective, open-label, observational study was to evaluate the possible effects of natalizumab on cognition and fatigue measures in RRMS patients treated for up to two years.
- Publication
PloS one, 2012, Vol 7, Issue 4, pe35843
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0035843