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- Title
Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders.
- Authors
Wegiel, Jerzy; Frackowiak, Janusz; Mazur-Kolecka, Bozena; Schanen, N Carolyn; Cook, Edwin H, Jr; Sigman, Marian; Brown, W Ted; Kuchna, Izabela; Wegiel, Jarek; Nowicki, Krzysztof; Imaki, Humi; Ma, Shuang Yong; Chauhan, Abha; Chauhan, Ved; Miller, David L; Mehta, Pankaj D; Flory, Michael; Cohen, Ira L; London, Eric; Reisberg, Barry; de Leon, Mony J; Wisniewski, Thomas
- Abstract
It has been shown that amyloid ß (Aβ), a product of proteolytic cleavage of the amyloid β precursor protein (APP), accumulates in neuronal cytoplasm in non-affected individuals in a cell type-specific amount.
- Publication
PloS one, 2012, Vol 7, Issue 5, pe35414
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0035414