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- Title
Accounting for a quantitative trait locus for plasma triglyceride levels: utilization of variants in multiple genes.
- Authors
Martin, Lisa J; Kissebah, Ahmed H; Olivier, Michael
- Abstract
For decades, research efforts have tried to uncover the underlying genetic basis of human susceptibility to a variety of diseases. Linkage studies have resulted in highly replicated findings and helped identify quantitative trait loci (QTL) for many complex traits; however identification of specific alleles accounting for linkage remains elusive. The purpose of this study was to determine whether with a sufficient number of variants a linkage signal can be fully explained.
- Publication
PloS one, 2012, Vol 7, Issue 4, pe34614
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0034614