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- Title
Small molecule antagonists of the Wnt/β-catenin signaling pathway target breast tumor-initiating cells in a Her2/Neu mouse model of breast cancer.
- Authors
Hallett, Robin M; Kondratyev, Maria K; Giacomelli, Andrew O; Nixon, Allison M L; Girgis-Gabardo, Adele; Ilieva, Dora; Hassell, John A
- Abstract
Recent evidence suggests that human breast cancer is sustained by a minor subpopulation of breast tumor-initiating cells (BTIC), which confer resistance to anticancer therapies and consequently must be eradicated to achieve durable breast cancer cure.
- Publication
PloS one, 2012, Vol 7, Issue 3, pe33976
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0033976