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- Title
AS03 adjuvanted AH1N1 vaccine associated with an abrupt increase in the incidence of childhood narcolepsy in Finland.
- Authors
Nohynek, Hanna; Jokinen, Jukka; Partinen, Markku; Vaarala, Outi; Kirjavainen, Turkka; Sundman, Jonas; Himanen, Sari-Leena; Hublin, Christer; Julkunen, Ilkka; Olsén, Päivi; Saarenpää-Heikkilä, Outi; Kilpi, Terhi
- Abstract
Narcolepsy is a chronic sleep disorder with strong genetic predisposition causing excessive daytime sleepiness and cataplexy. A sudden increase in childhood narcolepsy was observed in Finland soon after pandemic influenza epidemic and vaccination with ASO3-adjuvanted Pandemrix. No increase was observed in other age groups.
- Publication
PloS one, 2012, Vol 7, Issue 3, pe33536
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0033536