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- Title
WormScan: a technique for high-throughput phenotypic analysis of Caenorhabditis elegans.
- Authors
Mathew, Mark D; Mathew, Neal D; Ebert, Paul R
- Abstract
There are four main phenotypes that are assessed in whole organism studies of Caenorhabditis elegans; mortality, movement, fecundity and size. Procedures have been developed that focus on the digital analysis of some, but not all of these phenotypes and may be limited by expense and limited throughput. We have developed WormScan, an automated image acquisition system that allows quantitative analysis of each of these four phenotypes on standard NGM plates seeded with E. coli. This system is very easy to implement and has the capacity to be used in high-throughput analysis.
- Publication
PloS one, 2012, Vol 7, Issue 3, pe33483
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0033483