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- Title
Genetic variant of AMD1 is associated with obesity in urban Indian children.
- Authors
Tabassum, Rubina; Jaiswal, Alok; Chauhan, Ganesh; Dwivedi, Om Prakash; Ghosh, Saurabh; Marwaha, Raman K; Tandon, Nikhil; Bharadwaj, Dwaipayan
- Abstract
Hyperhomocysteinemia is regarded as a risk factor for cardiovascular diseases, diabetes and obesity. Manifestation of these chronic metabolic disorders starts in early life marked by increase in body mass index (BMI). We hypothesized that perturbations in homocysteine metabolism in early life could be a link between childhood obesity and adult metabolic disorders. Thus here we investigated association of common variants from homocysteine metabolism pathway genes with obesity in 3,168 urban Indian children.
- Publication
PloS one, 2012, Vol 7, Issue 4, pe33162
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0033162