We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Detection of IL28B SNP DNA from buccal epithelial cells, small amounts of serum, and dried blood spots.
- Authors
Halfon, Philippe; Ouzan, Denis; Khiri, Hacène; Pénaranda, Guillaume; Castellani, Paul; Oulès, Valerie; Kahloun, Asma; Amrani, Nolwenn; Fanteria, Lise; Martineau, Agnès; Naldi, Lou; Bourlière, Marc
- Abstract
Point mutations in the coding region of the interleukin 28 gene (rs12979860) have recently been identified for predicting the outcome of treatment of hepatitis C virus infection. This polymorphism detection was based on whole blood DNA extraction. Alternatively, DNA for genetic diagnosis has been derived from buccal epithelial cells (BEC), dried blood spots (DBS), and genomic DNA from serum. The aim of the study was to investigate the reliability and accuracy of alternative routes of testing for single nucleotide polymorphism allele rs12979860CC.
- Publication
PloS one, 2012, Vol 7, Issue 3, pe33000
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0033000