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- Title
Meta-analysis of two genome-wide association studies of bovine paratuberculosis.
- Authors
Minozzi, Giulietta; Williams, John L; Stella, Alessandra; Strozzi, Francesco; Luini, Mario; Settles, Matthew L; Taylor, Jeremy F; Whitlock, Robert H; Zanella, Ricardo; Neibergs, Holly L
- Abstract
Bovine paratuberculosis (ParaTB) also known as Johne's disease, is a contagious fatal disease resulting from infection by Mycobacterium avium subspecies paratuberculosis (MAP). Previous studies have identified loci associated with ParaTB using different measurements to define cases and controls. The objective of this study was to combine the data from two recent studies to identify genetic loci associated with MAP tissue infection and humoral immune response, defined by MAP ELISA-positive cattle, by comparing cases and control animals for one or both measures of infection.
- Publication
PloS one, 2012, Vol 7, Issue 3, pe32578
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0032578