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- Title
Inhibition of chondrosarcoma growth by mTOR inhibitor in an in vivo syngeneic rat model.
- Authors
Perez, Jennifer; Decouvelaere, Anne Valérie; Pointecouteau, Thomas; Pissaloux, Daniel; Michot, Jean Philippe; Besse, Anthony; Blay, Jean Yves; Dutour, Aurélie
- Abstract
Chondrosarcomas are the second most frequent primary malignant type of bone tumor. No effective systemic treatment has been identified in advanced or adjuvant phases for chondrosarcoma. The aim of the present study was to determine the antitumor effects of doxorubicin and everolimus, an mTOR inhibitor on chondrosarcoma progression.
- Publication
PloS one, 2012, Vol 7, Issue 6, pe32458
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0032458