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- Title
Identification of cancer cell-line origins using fluorescence image-based phenomic screening.
- Authors
Lee, Jun-Seok; Kim, Yun Kyung; Kim, Han Jo; Hajar, Siti; Tan, Yee Ling; Kang, Nam-Young; Ng, Shin Hui; Yoon, Chang No; Chang, Young-Tae
- Abstract
Universal phenotyping techniques that can discriminate among various states of biological systems have great potential. We applied 557 fluorescent library compounds to NCI's 60 human cancer cell-lines (NCI-60) to generate a systematic fluorescence phenotypic profiling data. By the kinetic fluorescence intensity analysis, we successfully discriminated the organ origin of all the 60 cell-lines.
- Publication
PloS one, 2012, Vol 7, Issue 2, pe32096
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0032096