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- Title
Reduced T regulatory cell response during acute Plasmodium falciparum infection in Malian children co-infected with Schistosoma haematobium.
- Authors
Lyke, Kirsten E; Dabo, Abdoulaye; Arama, Charles; Daou, Modibo; Diarra, Issa; Wang, Amy; Plowe, Christopher V; Doumbo, Ogobara K; Sztein, Marcelo B
- Abstract
Regulatory T cells (Tregs) suppress host immune responses and participate in immune homeostasis. In co-infection, secondary parasite infections may disrupt the immunologic responses induced by a pre-existing parasitic infection. We previously demonstrated that schistosomiasis-positive (SP) Malian children, aged 4-8 years, are protected against the acquisition of malaria compared to matched schistosomiasis-negative (SN) children.
- Publication
PloS one, 2012, Vol 7, Issue 2, pe31647
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0031647