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- Title
Neonatal neurobehavior and diffusion MRI changes in brain reorganization due to intrauterine growth restriction in a rabbit model.
- Authors
Eixarch, Elisenda; Batalle, Dafnis; Illa, Miriam; Muñoz-Moreno, Emma; Arbat-Plana, Ariadna; Amat-Roldan, Ivan; Figueras, Francesc; Gratacos, Eduard
- Abstract
Intrauterine growth restriction (IUGR) affects 5-10% of all newborns and is associated with a high risk of abnormal neurodevelopment. The timing and patterns of brain reorganization underlying IUGR are poorly documented. We developed a rabbit model of IUGR allowing neonatal neurobehavioral assessment and high resolution brain diffusion magnetic resonance imaging (MRI). The aim of the study was to describe the pattern and functional correlates of fetal brain reorganization induced by IUGR.
- Publication
PloS one, 2012, Vol 7, Issue 2, pe31497
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0031497