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- Title
Phylo: a citizen science approach for improving multiple sequence alignment.
- Authors
Kawrykow, Alexander; Roumanis, Gary; Kam, Alfred; Kwak, Daniel; Leung, Clarence; Wu, Chu; Zarour, Eleyine; Sarmenta, Luis; Blanchette, Mathieu; Waldispühl, Jérôme; Phylo players
- Abstract
Comparative genomics, or the study of the relationships of genome structure and function across different species, offers a powerful tool for studying evolution, annotating genomes, and understanding the causes of various genetic disorders. However, aligning multiple sequences of DNA, an essential intermediate step for most types of analyses, is a difficult computational task. In parallel, citizen science, an approach that takes advantage of the fact that the human brain is exquisitely tuned to solving specific types of problems, is becoming increasingly popular. There, instances of hard computational problems are dispatched to a crowd of non-expert human game players and solutions are sent back to a central server.
- Publication
PloS one, 2012, Vol 7, Issue 3, pe31362
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0031362