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- Title
Serotonin transporter polymorphism modulates N-back task performance and fMRI BOLD signal intensity in healthy women.
- Authors
Jonassen, Rune; Endestad, Tor; Neumeister, Alexander; Foss Haug, Kari Bente; Berg, Jens Petter; Landrø, Nils Inge
- Abstract
Exploring intermediate phenotypes within the human brain's functional and structural circuitry is a promising approach to explain the relative contributions of genetics, complex behaviors and neural mechanisms in the development of major depressive disorder (MDD). The polymorphic region 5-HTTLPR in the serotonin transporter gene (SLC6A4) has been shown to modulate MDD risk, but the neural underpinnings are incompletely understood.
- Publication
PloS one, 2012, Vol 7, Issue 1, pe30564
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0030564