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- Title
A multi-cohort study of polymorphisms in the GH/IGF axis and physical capability: the HALCyon programme.
- Authors
Alfred, Tamuno; Ben-Shlomo, Yoav; Cooper, Rachel; Hardy, Rebecca; Cooper, Cyrus; Deary, Ian J; Gaunt, Tom R; Gunnell, David; Harris, Sarah E; Kumari, Meena; Martin, Richard M; Sayer, Avan Aihie; Starr, John M; Kuh, Diana; Day, Ian N M; HALCyon study team
- Abstract
Low muscle mass and function have been associated with poorer indicators of physical capability in older people, which are in-turn associated with increased mortality rates. The growth hormone/insulin-like growth factor (GH/IGF) axis is involved in muscle function and genetic variants in genes in the axis may influence measures of physical capability.
- Publication
PloS one, 2012, Vol 7, Issue 1, pe29883
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0029883