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- Title
Intranasal immunization of the combined lipooligosaccharide conjugates protects mice from the challenges with three serotypes of Moraxella catarrhalis.
- Authors
Ren, Dabin; Xie, Hang; Zhang, Wenhong; Hassan, Ferdaus; Petralia, Ronald S; Yu, Shengqing; Lim, David J; Gu, Xin-Xing
- Abstract
There are no licensed vaccines available against Moraxella catarrhalis, a significant human respiratory pathogen. Lipooligosaccharide (LOS) based conjugate vaccines derived from individual serotype M. catarrhalis only showed partial protection coverage. A vaccine combining LOS conjugates of two or three serotypes might provide a broader protection.
- Publication
PloS one, 2011, Vol 6, Issue 12, pe29553
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0029553