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- Title
Regulation of cysteinyl leukotriene receptor 2 expression--a potential anti-tumor mechanism.
- Authors
Magnusson, Cecilia; Bengtsson, Astrid M; Liu, Minghui; Liu, Jian; Ceder, Yvonne; Ehrnström, Roy; Sjölander, Anita
- Abstract
The cysteinyl leukotrienes receptors (CysLTRs) are implicated in many different pathological conditions, such as inflammation and cancer. We have previously shown that colon cancer patients with high CysLT(1)R and low CysLT(2)R expression demonstrate poor prognosis. Therefore, we wanted to investigate ways for the transcriptional regulation of CysLT(2)R, which still remains to be poorly understood.
- Publication
PloS one, 2011, Vol 6, Issue 12, pe29060
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0029060