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- Title
Genome-scale screen for DNA methylation-based detection markers for ovarian cancer.
- Authors
Campan, Mihaela; Moffitt, Melissa; Houshdaran, Sahar; Shen, Hui; Widschwendter, Martin; Daxenbichler, Günter; Long, Tiffany; Marth, Christian; Laird-Offringa, Ite A; Press, Michael F; Dubeau, Louis; Siegmund, Kimberly D; Wu, Anna H; Groshen, Susan; Chandavarkar, Uma; Roman, Lynda D; Berchuck, Andrew; Pearce, Celeste L; Laird, Peter W
- Abstract
The identification of sensitive biomarkers for the detection of ovarian cancer is of high clinical relevance for early detection and/or monitoring of disease recurrence. We developed a systematic multi-step biomarker discovery and verification strategy to identify candidate DNA methylation markers for the blood-based detection of ovarian cancer.
- Publication
PloS one, 2011, Vol 6, Issue 12, pe28141
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0028141