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- Title
Heterogeneous nuclear ribonucleoprotein k interacts with Abi-1 at postsynaptic sites and modulates dendritic spine morphology.
- Authors
Proepper, Christian; Steinestel, Konrad; Schmeisser, Michael J; Heinrich, Jutta; Steinestel, Julie; Bockmann, Juergen; Liebau, Stefan; Boeckers, Tobias M
- Abstract
Abelson-interacting protein 1 (Abi-1) plays an important role for dendritic branching and synapse formation in the central nervous system. It is localized at the postsynaptic density (PSD) and rapidly translocates to the nucleus upon synaptic stimulation. At PSDs Abi-1 is in a complex with several other proteins including WASP/WAVE or cortactin thereby regulating the actin cytoskeleton via the Arp 2/3 complex.
- Publication
PloS one, 2011, Vol 6, Issue 11, pe27045
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0027045