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- Title
HIVsirDB: a database of HIV inhibiting siRNAs.
- Authors
Tyagi, Atul; Ahmed, Firoz; Thakur, Nishant; Sharma, Arun; Raghava, Gajendra P S; Kumar, Manoj
- Abstract
Human immunodeficiency virus (HIV) is responsible for millions of deaths every year. The current treatment involves the use of multiple antiretroviral agents that may harm patients due to their toxic nature. RNA interference (RNAi) is a potent candidate for the future treatment of HIV, uses short interfering RNA (siRNA/shRNA) for silencing HIV genes. In this study, attempts have been made to create a database HIVsirDB of siRNAs responsible for silencing HIV genes.
- Publication
PloS one, 2011, Vol 6, Issue 10, pe25917
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0025917