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- Title
Minor changes in the hemagglutinin of influenza A(H1N1)2009 virus alter its antigenic properties.
- Authors
Strengell, Mari; Ikonen, Niina; Ziegler, Thedi; Julkunen, Ilkka
- Abstract
The influenza A(H1N1)2009 virus has been the dominant type of influenza A virus in Finland during the 2009-2010 and 2010-2011 epidemic seasons. We analyzed the antigenic characteristics of several influenza A(H1N1)2009 viruses isolated during the two influenza seasons by analyzing the amino acid sequences of the hemagglutinin (HA), modeling the amino acid changes in the HA structure and measuring antibody responses induced by natural infection or influenza vaccination.
- Publication
PloS one, 2011, Vol 6, Issue 10, pe25848
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0025848