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- Title
Analysis of hypoxia and hypoxia-like states through metabolite profiling.
- Authors
Gleason, Julie E; Corrigan, David J; Cox, James E; Reddi, Amit R; McGinnis, Lauren A; Culotta, Valeria C
- Abstract
In diverse organisms, adaptation to low oxygen (hypoxia) is mediated through complex gene expression changes that can, in part, be mimicked by exposure to metals such as cobalt. Although much is known about the transcriptional response to hypoxia and cobalt, little is known about the all-important cell metabolism effects that trigger these responses.
- Publication
PloS one, 2011, Vol 6, Issue 9, pe24741
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0024741