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Title
Down-regulated NOD2 by immunosuppressants in peripheral blood cells in patients with SLE reduces the muramyl dipeptide-induced IL-10 production.
Authors
Yu, Shui-Lian; Wong, Chun-Kwok; Wong, Purple Tsz-Yan; Chen, Da-Peng; Szeto, Cheuk-Chun; Li, Edmund K; Tam, Lai-Shan
Abstract
Pattern recognition receptors (PRRs) such as Toll-like receptors are aberrantly expressed of peripheral blood mononuclear cells (PBMCs) in systemic lupus erythematosus (SLE) patients, for playing immunopathological roles.