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- Title
An atypical unfolded protein response in heat shocked cells.
- Authors
Heldens, Lonneke; Hensen, Sanne M M; Onnekink, Carla; van Genesen, Siebe T; Dirks, Ron P; Lubsen, Nicolette H
- Abstract
The heat shock response (HSR) and the unfolded protein response (UPR) are both activated by proteotoxic stress, although in different compartments, and share cellular resources. How these resources are allocated when both responses are active is not known. Insight in possible crosstalk will help understanding the consequences of failure of these systems in (age-related) disease.
- Publication
PloS one, 2011, Vol 6, Issue 8, pe23512
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0023512