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- Title
A double blind, placebo-controlled, randomized crossover study of the acute metabolic effects of olanzapine in healthy volunteers.
- Authors
Albaugh, Vance L; Singareddy, Ravi; Mauger, David; Lynch, Christopher J
- Abstract
Atypical antipsychotics exhibit metabolic side effects including diabetes mellitus and obesity. The adverse events are preceded by acute worsening of oral glucose tolerance (oGTT) along with reduced plasma free fatty acids (FFA) and leptin in animal models. It is unclear whether the same acute effects occur in humans.
- Publication
PloS one, 2011, Vol 6, Issue 8, pe22662
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0022662