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- Title
TCF7L2 polymorphism, weight loss and proinsulin:insulin ratio in the diabetes prevention program.
- Authors
McCaffery, Jeanne M; Jablonski, Kathleen A; Franks, Paul W; Dagogo-Jack, Sam; Wing, Rena R; Knowler, William C; Delahanty, Linda; Dabelea, Dana; Hamman, Richard; Shuldiner, Alan R; Florez, Jose C; Diabetes Prevention Program Research Group
- Abstract
TCF7L2 variants have been associated with type 2 diabetes, body mass index (BMI), and deficits in proinsulin processing and insulin secretion. Here we sought to test whether these effects were apparent in high-risk individuals and modify treatment responses.
- Publication
PloS one, 2011, Vol 6, Issue 7, pe21518
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0021518