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- Title
3',4'-Dihydroxyflavonol reduces superoxide and improves nitric oxide function in diabetic rat mesenteric arteries.
- Authors
Leo, Chen-Huei; Hart, Joanne L; Woodman, Owen L
- Abstract
3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant that acutely preserves nitric oxide (NO) activity in the presence of elevated reactive oxygen species (ROS). We hypothesized that DiOHF treatment (7 days, 1 mg/kg per day s.c.) would improve relaxation in mesenteric arteries from diabetic rats where endothelial dysfunction is associated with elevated oxidant stress.
- Publication
PloS one, 2011, Vol 6, Issue 6, pe20813
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0020813