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- Title
Genome-wide transcriptomic analysis of intestinal tissue to assess the impact of nutrition and a secondary nematode challenge in lactating rats.
- Authors
Athanasiadou, Spiridoula; Jones, Leigh A; Burgess, Stewart T G; Kyriazakis, Ilias; Pemberton, Alan D; Houdijk, Jos G M; Huntley, John F
- Abstract
Gastrointestinal nematode infection is a major challenge to the health and welfare of mammals. Although mammals eventually acquire immunity to nematodes, this breaks down around parturition, which renders periparturient mammals susceptible to re-infection and an infection source for their offspring. Nutrient supplementation reduces the extent of periparturient parasitism, but the underlying mechanisms remain unclear. Here, we use a genome wide approach to assess the effects of protein supplementation on gene expression in the small intestine of periparturient rats following nematode re-infection.
- Publication
PloS one, 2011, Vol 6, Issue 6, pe20771
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0020771