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- Title
No association of xenotropic murine leukemia virus-related viruses with prostate cancer.
- Authors
Switzer, William M; Jia, Hongwei; Zheng, Haoqiang; Tang, Shaohua; Heneine, Walid
- Abstract
The association of the xenotropic murine leukemia virus-related virus (XMRV) with prostate cancer continues to receive heightened attention as studies report discrepant XMRV prevalences ranging from zero up to 23%. It is unclear if differences in the diagnostic testing, disease severity, geography, or other factors account for the discordant results. We report here the prevalence of XMRV in a population with well-defined prostate cancers and RNase L polymorphism. We used broadly reactive PCR and Western blot (WB) assays to detect infection with XMRV and related murine leukemia viruses (MLV).
- Publication
PloS one, 2011, Vol 6, Issue 5, pe19065
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0019065