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- Title
Carotid plaque age is a feature of plaque stability inversely related to levels of plasma insulin.
- Authors
Hägg, Sara; Salehpour, Mehran; Noori, Peri; Lundström, Jesper; Possnert, Göran; Takolander, Rabbe; Konrad, Peter; Rosfors, Stefan; Ruusalepp, Arno; Skogsberg, Josefin; Tegnér, Jesper; Björkegren, Johan
- Abstract
The stability of atherosclerotic plaques determines the risk for rupture, which may lead to thrombus formation and potentially severe clinical complications such as myocardial infarction and stroke. Although the rate of plaque formation may be important for plaque stability, this process is not well understood. We took advantage of the atmospheric (14)C-declination curve (a result of the atomic bomb tests in the 1950s and 1960s) to determine the average biological age of carotid plaques.
- Publication
PloS one, 2011, Vol 6, Issue 4, pe18248
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0018248