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- Title
Early and prolonged antiretroviral therapy is associated with an HIV-1-specific T-cell profile comparable to that of long-term non-progressors.
- Authors
Cellerai, Cristina; Harari, Alexandre; Stauss, Hans; Yerly, Sabine; Geretti, Anna-Maria; Carroll, Anne; Yee, Thynn; Ainsworth, Jonathan; Williams, Ian; Sweeney, John; Freedman, Andrew; Johnson, Margaret; Pantaleo, Giuseppe; Kinloch-de Loes, Sabine
- Abstract
Intervention with antiretroviral treatment (ART) and control of viral replication at the time of HIV-1 seroconversion may curtail cumulative immunological damage. We have therefore hypothesized that ART maintenance over a very prolonged period in HIV-1 seroconverters could induce an immuno-virological status similar to that of HIV-1 long-term non-progressors (LTNPs).
- Publication
PloS one, 2011, Vol 6, Issue 4, pe18164
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0018164