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- Title
Circadian rhythm and cartilage extracellular matrix genes in osseointegration: a genome-wide screening of implant failure by vitamin D deficiency.
- Authors
Mengatto, Cristiane Machado; Mussano, Federico; Honda, Yoshitomo; Colwell, Christopher S; Nishimura, Ichiro
- Abstract
Successful dental and orthopedic implants require the establishment of an intimate association with bone tissue; however, the mechanistic explanation of how biological systems accomplish osseointegration is still incomplete. We sought to identify critical gene networks involved in osseointegration by exploring the implant failure model under vitamin D deficiency.
- Publication
PloS one, 2011, Vol 6, Issue 1, pe15848
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0015848