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- Title
Large-scale candidate gene analysis of HDL particle features.
- Authors
Kaess, Bernhard M; Tomaszewski, Maciej; Braund, Peter S; Stark, Klaus; Rafelt, Suzanne; Fischer, Marcus; Hardwick, Robert; Nelson, Christopher P; Debiec, Radoslaw; Huber, Fritz; Kremer, Werner; Kalbitzer, Hans Robert; Rose, Lynda M; Chasman, Daniel I; Hopewell, Jemma; Clarke, Robert; Burton, Paul R; Tobin, Martin D; Hengstenberg, Christian; Samani, Nilesh J
- Abstract
HDL cholesterol (HDL-C) is an established marker of cardiovascular risk with significant genetic determination. However, HDL particles are not homogenous, and refined HDL phenotyping may improve insight into regulation of HDL metabolism. We therefore assessed HDL particles by NMR spectroscopy and conducted a large-scale candidate gene association analysis.
- Publication
PloS one, 2011, Vol 6, Issue 1, pe14529
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0014529