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- Title
TIA-1 cytotoxic granule-associated RNA binding protein improves the prognostic performance of CD8 in mismatch repair-proficient colorectal cancer.
- Authors
Zlobec, Inti; Karamitopoulou, Eva; Terracciano, Luigi; Piscuoglio, Salvatore; Iezzi, Giandomenica; Muraro, Manuele Giuseppe; Spagnoli, Giulio; Baker, Kristi; Tzankov, Alexandar; Lugli, Alessandro
- Abstract
Evidence suggests a confounding effect of mismatch repair (MMR) status on immune response in colorectal cancer. The identification of innate and adaptive immune cells, that can complement the established prognostic effect of CD8 in MMR-proficient colorectal cancers patients, representing 85% of all cases, has not been performed.
- Publication
PloS one, 2010, Vol 5, Issue 12, pe14282
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0014282