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- Title
Yeast biological networks unfold the interplay of antioxidants, genome and phenotype, and reveal a novel regulator of the oxidative stress response.
- Authors
Otero, Jose M; Papadakis, Manos A; Udatha, D B R K Gupta; Nielsen, Jens; Panagiotou, Gianni
- Abstract
Identifying causative biological networks associated with relevant phenotypes is essential in the field of systems biology. We used ferulic acid (FA) as a model antioxidant to characterize the global expression programs triggered by this small molecule and decipher the transcriptional network controlling the phenotypic adaptation of the yeast Saccharomyces cerevisiae.
- Publication
PloS one, 2010, Vol 5, Issue 10, pe13606
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0013606