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Title
Xenopus egg extracts increase dynamics of histone H1 on sperm chromatin.
Authors
Freedman, Benjamin S; Miller, Kelly E; Heald, Rebecca
Abstract
Linker histone H1 has been studied in vivo and using reconstituted chromatin, but there have been few systematic studies of the effects of the cellular environment on its function. Due to the presence of many other chromatin factors and specific chaperones such as RanBP7/importin beta that regulate histone H1, linker histones likely function differently in vivo than in purified systems.