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- Title
Hepatitis C virus core protein induces neuroimmune activation and potentiates Human Immunodeficiency Virus-1 neurotoxicity.
- Authors
Vivithanaporn, Pornpun; Maingat, Ferdinand; Lin, Liang-Tzung; Na, Hong; Richardson, Christopher D; Agrawal, Babita; Cohen, Eric A; Jhamandas, Jack H; Power, Christopher
- Abstract
Hepatitis C virus (HCV) genomes and proteins are present in human brain tissues although the impact of HIV/HCV co-infection on neuropathogenesis remains unclear. Herein, we investigate HCV infectivity and effects on neuronal survival and neuroinflammation in conjunction with HIV infection.
- Publication
PloS one, 2010, Vol 5, Issue 9, pe12856
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0012856