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Title
Pharmacologic inhibition of COX-1 and COX-2 in influenza A viral infection in mice.
Authors
Carey, Michelle A; Bradbury, J Alyce; Rebolloso, Yvette D; Graves, Joan P; Zeldin, Darryl C; Germolec, Dori R
Abstract
We previously demonstrated that cyclooxygenase (COX)-1 deficiency results in greater morbidity and inflammation, whereas COX-2 deficiency leads to reduced morbidity, inflammation and mortality in influenza infected mice.