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- Title
The complete genome sequence of the pathogenic intestinal spirochete Brachyspira pilosicoli and comparison with other Brachyspira genomes.
- Authors
Wanchanthuek, Phatthanaphong; Bellgard, Matthew I; La, Tom; Ryan, Karon; Moolhuijzen, Paula; Chapman, Brett; Black, Michael; Schibeci, David; Hunter, Adam; Barrero, Roberto; Phillips, Nyree D; Hampson, David J
- Abstract
The anaerobic spirochete Brachyspira pilosicoli colonizes the large intestine of various species of birds and mammals, including humans. It causes "intestinal spirochetosis", a condition characterized by mild colitis, diarrhea and reduced growth. This study aimed to sequence and analyse the bacterial genome to investigate the genetic basis of its specialized ecology and virulence.
- Publication
PloS one, 2010, Vol 5, Issue 7, pe11455
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0011455