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- Title
Dendritic cells in chronic mycobacterial granulomas restrict local anti-bacterial T cell response in a murine model.
- Authors
Schreiber, Heidi A; Hulseberg, Paul D; Lee, JangEun; Prechl, Jozsef; Barta, Peter; Szlavik, Nora; Harding, Jeffrey S; Fabry, Zsuzsanna; Sandor, Matyas
- Abstract
Mycobacterium-induced granulomas are the interface between bacteria and host immune response. During acute infection dendritic cells (DCs) are critical for mycobacterial dissemination and activation of protective T cells. However, their role during chronic infection in the granuloma is poorly understood.
- Publication
PloS one, 2010, Vol 5, Issue 7, pe11453
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0011453